TY - JOUR AU - Fonseca Velasquez, Aldemar PY - 2014/01/03 Y2 - 2024/03/29 TI - Behavioral model of a basic trabecular-bone multi-cellular unit using cellular automaton JF - Visión electrónica JA - Vis. Electron. VL - 8 IS - 1 SE - Visión Investigadora DO - 10.14483/22484728.7855 UR - https://revistas.udistrital.edu.co/index.php/visele/article/view/7855 SP - 6-18 AB - <p>Bone remodeling is the biological process through which old bone tissue is transformed into new bone through the action of a basic unit of bone remodeling (BMU). This paper presents a computational model to determine the variation of cell population caused by the presence of micro-fractures within the BMU during the remodeling process, also determines the spatial evolution at particular points of the trabecular bone surface. The remodeling process presented is governed by a twodimensional cellular automaton that evolves according to a set of rules and states, based on biological processes that occur in bone remodeling. The simulation of the remodeling process, programmed in MATLAB® performed in time intervals of 0.3 seconds, in the model showed a ratio of 20 osteoclasts to 190 osteoblasts. On the other hand, an approximate resorption time of 34 days and 150 days for formation was obtained. Bone mass showed a maximum percentage loss of 19%.</p> ER -