Publicado:
2023-01-30Número:
Vol. 17 Núm. 1 (2023)Sección:
Visión InvestigadoraEvolución del uso de nanopartículas en diagnóstico y tratamiento del cáncer
Evolution of the use of nanoparticles in cancer diagnosis and treatment
Palabras clave:
Fluido biomagnético, Nanopartículas, Nanopártículas magnéticas, SPIONs (es).Palabras clave:
Biomagnetic fluid, Nanoparticles, Magnetic nanoparticles, SPIONs (en).Descargas
Resumen (es)
El uso de nanopartículas en el área de la salud es un tema de investigación que ha venido incrementándose en los últimos años, desde esa perspectiva este trabajo se centró en hacer una caracterización de las nanopartículas, su evolución e interacción con la sangre, aspecto abordado a través de la descripción del fluido biomagnético, centrándonos en características como viscosidad y la geometría. También, se da a conocer la evolución de las aplicaciones o técnicas en las cuales se han venido empleando las nanopartículas, enfocando la revisión realizada en tratamientos contra el cáncer, para lo cual se consideraron las cuatro generaciones progresivas de este campo investigativo, así como el uso de las nanopartículas en imágenes diagnósticas. Finalmente se identificaron algunos campos de implementación y estudio en Colombia. La revisión realizada permite concluir que la evolución del empleo de las nanopartículas en aplicaciones médicas ha posibilitado la realización de tratamientos de cáncer focalizados; en ese sentido se reconoce la incidencia de los SPIONs en los avances logrados recientemente, así como la importancia de profundizar en el estudio del movimiento de estas partículas.
Resumen (en)
The use of nanoparticles in the health area is a research topic that has been increasing in recent years, from that perspective this work focused on making a characterization of nanoparticles, their evolution and interaction with blood, aspect addressed through the description of the biomagnetic fluid, focusing on characteristics such as viscosity and geometry. Also, the evolution of the applications or techniques in which nanoparticles have been used is presented, focusing the review on cancer treatments, for which the four progressive generations of this research field were considered, as well as the use of nanoparticles in diagnostic imaging. Finally, some fields of implementation and study in Colombia were identified. The review carried out allows concluding that the evolution of the use of nanoparticles in medical applications has made possible the realization of targeted cancer treatments; in this sense, the incidence of SPIONs in the advances achieved recently is recognized, as well as the importance of deepening the study of the movement of these particles.
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